Clinical Efficacy and Safety Profile of Combined Therapy
Be cautious when standing up from sitting or lying to prevent dizziness. Grapefruit juice is one of the drinks that might increase the level of dapoxetine in the blood, heightening the risk of side effects. Men with significant ischemic heart disease, sick sinus syndrome, a history of mania or severe depression (major depressive disorder), if already on tricyclic antidepressants, or those with severe renal impairment should avoid taking Priligy. Adverse effects associated with dapoxetine range from nausea, dizziness, and headaches to increased blood pressure.
| Medication | Available Forms | Typical Dose Range | Packaging Options |
|---|---|---|---|
| Dapoxetine | Tablets | 30 mg, 60 mg | Pack of 10, 30, 60 pills |
| Tadalafil | Tablets | 5 mg, 10 mg, 20 mg | Bottles with 10–30 tablets |
| Dapoxetine | Oral tablets | 30 mg, 60 mg | Blister packs |
| Tadalafil | Oral disintegrating tablets | 10 mg, 20 mg | Single-dose packs |
While most of these adverse reactions are mild, it's essential to recognize and report any severe adverse reactions immediately.
- Pharmacodynamics studies illustrate how these drugs work synergistically.
- Dapoxetine inhibits serotonin transporters increasing ejaculatory threshold.
- Tadalafil enhances nitric oxide-mediated vasodilation to improve erections.
- Both drugs improve sexual performance through different mechanisms.
- Pharmacokinetic profiles support co-administration without significant interference.
- Safety margins are well established in clinical dosing ranges.
- Drug interaction studies help define contraindications and precautions.
- Metabolism primarily occurs via CYP3A4 enzyme for both drugs.
- Understanding these details aids prescribers in optimizing therapy.
Clinical trials have not conclusively linked dapoxetine to alterations in testosterone levels. However, always consult with a specialist in sexual medicine for comprehensive insights. Dapoxetine, under the brand name Priligy, has been patented in the UK, allowing only certain distributors access.
References (29)
Administration of this medicine to patients using any form of organic nitrate is contraindicated. Tadalafil was shown to potentiate the hypotensive effect of nitrates. Administration of this medicine to patients with significant pathological cardiac conditions is contraindicated. A history of mania or severe depression. Concomitant treatment with Thioridazine, or within 14 days of discontinuing treatment with Thioridazine.
World J. Pharm. Pharm. Sci.
Similarly, Thioridazine should not be administered within 7 days after Tadalafil Dapoxetine tablets have been discontinued. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Concomitant treatment with serotonin reuptake inhibitors [selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs)] or other medicinal/herbal products with serotonergic effects [e.g., L- tryptophan, triptans, tramadol, linezolid, lithium, St. John's Wort (Hypericum perforatum)] or within 14 days of discontinuing treatment with these medicinal/herbal products. Similarly, these medicinal/herbal products should not be administered within 7 days after this medicine has been discontinued. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Concomitant treatment of potent CYP3A4 inhibitors such as Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Telithromycin, Nefazadone, Nelfinavir, Atazanavir, etc.
Neurocognitive safety
Do not use Tadalafil Dapoxetine tablets in patients who are using a GC stimulator, such as Riociguat. Tadalafil may potentiate the hypotensive effects of GC stimulators. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Storage Instructions Tadalafil Dapoxetine Tablets have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. However, more affordable generics are expected to surface post-patent expiry (2024), providing a more cost-effective solution. Certain NHS areas do indeed offer Priligy prescriptions. Connecting with a local GP for details on NHS and private prescription options is always advised. Dapoxetine increases the intravaginal ejaculatory latency time, though exact times can vary based on individual responses. Dapoxetine has undergone placebo-controlled clinical trials, with results indicating a high satisfaction rate. Most men reported an improvement in premature ejaculation symptoms and a reduction in personal distress related to ejaculation. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil and Dapoxetine Combination medication is a combination containing Tadalafil 20mg and Dapoxetine 60mg in a single tablet. Tadalafil Dapoxetine Tablets are used for the treatment of male erectile dysfunction as well as treatment of premature ejaculation in men at the same time. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Dapoxetine Hydrochloride is used to treat premature ejaculation in adult men aged 18 to 64 years. Dapoxetine increases the time it takes to ejaculate and can improve the control over the ejaculation.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 5mg | 10 Pills | 29.39€ 27.99€ | |
| Priligy Generic Dapoxetine | 60mg | 20 + 4 Pills | 77.31€ 73.63€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Priligy Generic Dapoxetine | 60mg | 180 + 10 Pills | 494.76€ 471.20€ | |
| Viagra Original | 100mg | 8 Pills | 59.84€ 56.99€ | |
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Priligy Generic Dapoxetine | 60mg | 10 Pills | 47.63€ 45.36€ | |
| Priligy Generic Dapoxetine | 60mg | 90 + 10 Pills | 265.64€ 252.99€ | |
| Cialis Generic | 60mg | 120 + 8 Pills | 240.18€ 228.74€ | |
| Priligy Generic Dapoxetine | 60mg | 60 + 8 Pills | 183.06€ 174.34€ | |
| Viagra Professional | 100mg | 20 Pills | 71.14€ 67.75€ | |
| Levitra Generic | 10mg | 60 + 6 Pills | 112.98€ 107.60€ | |
| Cialis Super Active | 20mg | 10 Pills | 55.64€ 52.99€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ | |
| Kamagra Polo | 100mg | 180 + 8 Pills | 446.52€ 425.26€ | |
| Cialis Original | 20mg | 14 + 2 Pills | 95.75€ 91.19€ |
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets – Brand Names Tadalafil Dapoxetine combination tablets tablets are available as Tadali Superb Tablets, Duraplus Tablets, Super Vidalista Tablets, Super Tadalista Tablets, Super Tadalis SX Tablets and Super Tadarise Tablets. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Active Ingredients The active ingredients contained in Tadalafil Dapoxetine tablets are Tadalafil and Dapoxetine Hydrochloride.
| Medication | Primary Use | Typical Conditions Treated | Notes |
|---|---|---|---|
| Dapoxetine | Premature ejaculation | Early ejaculatory control | Taken on demand before sex |
| Tadalafil | Erectile dysfunction | Inability to maintain an erection | Taken as needed or daily |
| Dapoxetine | Treatment of serotonin reuptake inhibitor (SSRI) side effects | Delays ejaculation | Prescribed with counseling |
| Tadalafil | Benign prostatic hyperplasia (BPH) | Urinary symptoms in BPH | Dose varies based on condition |
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Chemical Structure The structure of Tadalafil is given below: © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Chemical Structure The structure of Dapoxetine is given below: © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadali Superb Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadali Superb Tablets Manufactured By: Alpha-Pharma Healthcare Private Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Tadali Superb Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Vidalista Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Vidalista Tablets Manufactured By: Centurion Laboratories Private Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Super Vidalista Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Tadalis SX Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Tadalis SX Tablets Manufactured By: Ajanta Pharma Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Tadalis SX Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Uses of Tadalafil and Dapoxetine Tablets The medical effect produced by Tadalafil Dapoxetine tablets is due to it's two components: Tadalafil and Dapoxetine Hydrochloride. Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor used for the treatment of Erectile Dysfunction (ED).
Drug Profile Summary
Be cautious when standing up from sitting or lying to prevent dizziness. Grapefruit juice is one of the drinks that might increase the level of dapoxetine in the blood, heightening the risk of side effects. Men with significant ischemic heart disease, sick sinus syndrome, a history of mania or severe depression (major depressive disorder), if already on tricyclic antidepressants, or those with severe renal impairment should avoid taking Priligy. Adverse effects associated with dapoxetine range from nausea, dizziness, and headaches to increased blood pressure. While most of these adverse reactions are mild, it's essential to recognize and report any severe adverse reactions immediately.
ATC (Anatomical Therapeutic Chemical Classification)
Clinical trials have not conclusively linked dapoxetine to alterations in testosterone levels. However, always consult with a specialist in sexual medicine for comprehensive insights. Dapoxetine, under the brand name Priligy, has been patented in the UK, allowing only certain distributors access. However, more affordable generics are expected to surface post-patent expiry (2024), providing a more cost-effective solution. Certain NHS areas do indeed offer Priligy prescriptions.
Rare but Serious Side Effects
Connecting with a local GP for details on NHS and private prescription options is always advised. Dapoxetine increases the intravaginal ejaculatory latency time, though exact times can vary based on individual responses. Dapoxetine has undergone placebo-controlled clinical trials, with results indicating a high satisfaction rate. Most men reported an improvement in premature ejaculation symptoms and a reduction in personal distress related to ejaculation. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil and Dapoxetine Combination medication is a combination containing Tadalafil 20mg and Dapoxetine 60mg in a single tablet. Dapoxetine Hydrochloride is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Dapoxetine Hydrochloride should only be prescribed to patients who meet all the following criteria: An intravaginal ejaculatory latency time (IELT) of less than two minutes; and persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes; and marked personal distress or interpersonal difficulty as a consequence of PE; and poor control over ejaculation as well as a history of premature ejaculation in the majority of intercourse attempts over the prior 6 months. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Recommended Adult Dosage The dose of Tadalafil and Dapoxetine Combination medication is orally one tablet once a day, with or without meals.
- Psychological effects include reduced anxiety and improved sexual satisfaction.
- Effectiveness may vary depending on individual health status and age.
- Dapoxetine's effect on ejaculation delay is usually up to 2-3 hours.
- Tadalafil improves erectile function allowing for more spontaneous activity.
- Patients should report any prolonged erection lasting over 4 hours immediately.
- Sexual stimulation is necessary for tadalafil to work effectively.
- Avoid grapefruit juice which can interfere with drug metabolism.
- Regular follow-up helps in adjusting dosage and monitoring side effects.
- Combining these tablets should not be confused with aphrodisiac or recreational use.
The tablet has to be administered one to three hours before sexual activity. Do not take more than 1 tablet in any 24 hour period.
| Medication Class | Interaction Type | Potential Effect | Notes |
|---|---|---|---|
| CYP3A4 inhibitors | Increased drug levels | Higher risk of side effects | e.g., ketoconazole, ritonavir |
| Nitrates | Severe hypotension | Dangerous blood pressure drop | Contraindicated |
| Alcohol | Increased sedation | Dizziness, hypotension | Use with caution |
| Antihypertensive medications | Additive blood pressure lowering | Risk of hypotension | Monitor blood pressure |
At least 24 hours should pass before you take the next dose.
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Tadalafil Dapoxetine Tablets are used for the treatment of male erectile dysfunction as well as treatment of premature ejaculation in men at the same time. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Dapoxetine Hydrochloride is used to treat premature ejaculation in adult men aged 18 to 64 years. Dapoxetine increases the time it takes to ejaculate and can improve the control over the ejaculation. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets – Brand Names Tadalafil Dapoxetine combination tablets tablets are available as Tadali Superb Tablets, Duraplus Tablets, Super Vidalista Tablets, Super Tadalista Tablets, Super Tadalis SX Tablets and Super Tadarise Tablets.
Pharmacokinetic and pharmacodynamic features of dapoxetine, a novel drug for ‘on-demand’ treatment of premature ejaculation
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Active Ingredients The active ingredients contained in Tadalafil Dapoxetine tablets are Tadalafil and Dapoxetine Hydrochloride. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Chemical Structure The structure of Tadalafil is given below: © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Chemical Structure The structure of Dapoxetine is given below: © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadali Superb Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadali Superb Tablets Manufactured By: Alpha-Pharma Healthcare Private Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Tadali Superb Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Vidalista Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Vidalista Tablets Manufactured By: Centurion Laboratories Private Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Super Vidalista Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Tadalis SX Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Super Tadalis SX Tablets Manufactured By: Ajanta Pharma Limited, India Strengths Available: Strengths Available: 80 mg ( Tadalafil 20mg and Dapoxetine Hydrochloride 60mg) More details on Tadalis SX Tablets © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Uses of Tadalafil and Dapoxetine Tablets The medical effect produced by Tadalafil Dapoxetine tablets is due to it's two components: Tadalafil and Dapoxetine Hydrochloride. Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor used for the treatment of Erectile Dysfunction (ED). Dapoxetine Hydrochloride is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Dapoxetine Hydrochloride should only be prescribed to patients who meet all the following criteria: An intravaginal ejaculatory latency time (IELT) of less than two minutes; and persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes; and marked personal distress or interpersonal difficulty as a consequence of PE; and poor control over ejaculation as well as a history of premature ejaculation in the majority of intercourse attempts over the prior 6 months.
Chemical Formula
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Recommended Adult Dosage The dose of Tadalafil and Dapoxetine Combination medication is orally one tablet once a day, with or without meals. The tablet has to be administered one to three hours before sexual activity. Do not take more than 1 tablet in any 24 hour period. At least 24 hours should pass before you take the next dose. © Clearsky sildenafil dapoxetine tablets Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Tadalafil Dapoxetine tablets are contraindicated in patients with a known hypersensitivity to Tadalafil, Dapoxetine Hydrochloride or any component of the tablet. © Clearsky sildenafil dapoxetine tablets Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Tadalafil Dapoxetine tablets are contraindicated in patients with a known hypersensitivity to Tadalafil, Dapoxetine Hydrochloride or any component of the tablet. Administration of this medicine to patients using any form of organic nitrate is contraindicated. Tadalafil was shown to potentiate the hypotensive effect of nitrates. Administration of this medicine to patients with significant pathological cardiac conditions is contraindicated. A history of mania or severe depression. Concomitant treatment with Thioridazine, or within 14 days of discontinuing treatment with Thioridazine. Similarly, Thioridazine should not be administered within 7 days after Tadalafil Dapoxetine tablets have been discontinued. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Concomitant treatment with serotonin reuptake inhibitors [selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs)] or other medicinal/herbal products with serotonergic effects [e.g., L- tryptophan, triptans, tramadol, linezolid, lithium, St. John's Wort (Hypericum perforatum)] or within 14 days of discontinuing treatment with these medicinal/herbal products. Similarly, these medicinal/herbal products should not be administered within 7 days after this medicine has been discontinued.
Additional information
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets - Warnings Patients should not use Tadalafil Dapoxetine tablets if sex is inadvisable due to cardiovascular status. Use of Tadalafil Dapoxetine tablets with alpha blockers, antihypertensives or substantial amounts of alcohol (5 units or greater) may lead to hypotension. This medicine is not recommended in combination with alpha blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when Tadalafil Dapoxetine tablets are used as a treatment for ED in men taking alpha blockers. Tadalafil Dapoxetine tablets are not suitable and should not be used if taking potent inhibitors of CYP3A4.
Chaudhari, Prof. Dr. Dhrubo Jyoti Sen and Prof. Dr. C. N. Patel, Development and validation of HPTLC method for Simultaneous estimation of avanafil and dapoxetine HCl in tablet dosage form
© Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets - Warnings Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Tadalafil Dapoxetine tablets with caution in patients predisposed to priapism. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Contraindications Concomitant treatment of potent CYP3A4 inhibitors such as Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Telithromycin, Nefazadone, Nelfinavir, Atazanavir, etc.
- Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI).
- Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor aiding erection.
- This combination is not suitable for women or children.
- The usual starting dose for dapoxetine is 30 mg, may increase to 60 mg if needed.
- Tadalafil doses vary between 5 mg daily or 10-20 mg as needed.
- Both drugs are metabolized in the liver; liver function should be monitored.
- Dapoxetine should not be taken with other SSRIs or MAO inhibitors.
- Tadalafil use is contraindicated in severe heart or kidney disease.
- Storage of tablets requires a cool, dry place away from sunlight.
Do not use Tadalafil Dapoxetine tablets in patients who are using a GC stimulator, such as Riociguat. Tadalafil may potentiate the hypotensive effects of GC stimulators. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Storage Instructions Tadalafil Dapoxetine Tablets have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets - Warnings Patients should not use Tadalafil Dapoxetine tablets if sex is inadvisable due to cardiovascular status. Use of Tadalafil Dapoxetine tablets with alpha blockers, antihypertensives or substantial amounts of alcohol (5 units or greater) may lead to hypotension. This medicine is not recommended in combination with alpha blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when Tadalafil Dapoxetine tablets are used as a treatment for ED in men taking alpha blockers.
Declaration of competing interest
Tadalafil Dapoxetine tablets are not suitable and should not be used if taking potent inhibitors of CYP3A4. © Clearsky Pharmacy TadalafilDapoxetine Tablets to treat Erectile Dysfunction and Premature Ejaculation at the Same Time Tadalafil Dapoxetine Tablets - Warnings Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Tadalafil Dapoxetine tablets with caution in patients predisposed to priapism.